The search options available allow for both simple text and complex searching across the database. In turn, the more uniform data support complex queries about macromolecular structure and provide more dependable results.
This system facilitates faster and more accurate data processing. The RCSB has improved the PDB by creating an integrated system for data intake and data distribution. The combined qualifications of its members have allowed the RCSB to increase the scope of PDB services without an increase in funding. Rutgers processes and annotates the data deposited SDSC integrates the databases and distributes the information and NIST oversees data uniformity, evaluation and archiving. PDB responsibilities have been divided among the institutions to take advantage of their expertise. In addition to Rutgers, Phil Bourne, senior principal scientist, leads a team at the San Diego Supercomputer Center (SDSC), a research unit of the University of California, San Diego and Gary Gilliland, chief of the Biotechnology Division, leads the RCSB team at the National Institute of Standards and Technology (NIST) in Gaithersburg, Md.
X particles 4 pdb upgrade#
The RCSB brings together experts from fields ranging from high-performance computing to bioinformatics to structural biology to fully integrate and upgrade all aspects of the Protein Data Base. The RCSB is directed by Helen Berman, a professor of chemistry at Rutgers, the State University of New Jersey, and principal investigator for the Protein Data Base project. Via the Web, database users in academia, government and industry access archival services and formulate complex queries that will provide reliable answers to further their research efforts. The RCSB's PDB gives researchers access to more information about biological structures from a single source than ever before. This requires very precise and accurate information on the atomic structure of complex molecules.
Medical researchers envision gaining new insights on the causes, effects and treatment of many diseases by unlocking the disease-fighting potential of biological macromolecules. The three-dimensional structures of proteins and other biological macromolecules contained in the PDB hold significant promise for the pharmaceutical and biotechnology industries in the search for new drugs with few or no side effects and the effort to understand the mystery of human disease. "With the advent of many new protein structures, I anticipate that implementation of modern database technologies by the RCSB will yield important dividends for all of molecular and cellular biology." Burley, Furlaud Professor at The Rockefeller University and Investigator in the Howard Hughes Medical Institute. "The PDB is an enormously important resource for biomedical research, and it is gratifying to learn that the move from Brookhaven National Laboratory to the RCSB has been seamless," said Dr. The success of these developments has accelerated the transition timetable. Since the RCSB began assuming responsibility for the PDB, data deposited by users has been turned around in record time, and new tools now provide a broader range of search and reporting options.
X particles 4 pdb archive#
The PDB, the nonprofit international archive for biomolecular structures used in pharmaceutical and medical research, has provided substantial improvements in service during the past few months.
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